This study focused on assessing the factors influencing Higher learning students’ perceptions on business mathematics performance focusing on the College of Business Education (CBE) Mwanza campus. The specific objectives were to examine the effect of gender on the way College students perceive Business mathematics and how these perceptions influence their performance and the second objective was to examine the relationship between six perception constructs and student’s performance in business Mathematics namely motivation, myths and beliefs, self confidence, family background and support, interest and teaching and learning materials used in business mathematics. Data were analyzed through correlation and regression analysis and the results revealed that all the six perception constructs had a positive and significant relationship with student’s performance in business mathematics. The study concludes that the six perceptions constructs had a positive and significant effect on student’s performance in business mathematics. The study recommends that both the management and the students at the CBE should work together in making sure that these perceptions are addressed fully for better performance of the institution and the students at large