This study assessed intrinsic and extrinsic factors that influenced nurses’ job satisfaction at respective Hospital and related each group of factors with overall nurses’ job satisfaction. Data were collected from a purposive and judgmental sample of 75 respondents a structured questionnaire. The questionnaire consisted of items from Warr-Cook and Wall’s Job Satisfaction Scale. Data analysis was conducted by using means, standard deviation and Pearson Product Moment Correlation (r) using Statistical Package for Social Science Version 20s. Results revealed that job security was an intrinsic factor which influenced respondents’ job satisfaction while extrinsic factors which played similar role consisted of co- worker relations and immediate supervisor. Most of the intrinsic and extrinsic factors were creating job dissatisfaction and overall, respondents were dissatisfied with their job. However, correlation results revealed that both intrinsic and extrinsic factors were significant and positively related with nurses’ overall job satisfaction (r = 0.673; .711; p <0.05). Based on these results, the study recommends to the Ministry of Health, Community Development, Gender, Elderly and Children to design and implement policies which seek solution to job dissatisfaction by improving dissatisfied intrinsic and extrinsic factors at the Hospital.